Crank 2 High Voltage begins with a professional assassin Chon Chelios kidnapped by a group of Chinese Gangster. In order to survive and feed this heart, Chelios must regularly load high voltage into people. The purpose of this gangster group is to use Chelios as a tool to fulfill the dark intentions set by them. However, they face the ultimate resistance of human will, of the instinct to exist freely in the individual Chelios.